Sophie Quinn - Female

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Sophie Quinn posted a blog.

TNF-a and LDH

TNF-а, among other cytokines, initiates a wide spectrum of biological activities that help activate the host’s response to infection, and thus may play pathophysiologic roles in PPE. Odeh et al measur...

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November 18, 2014 11:00 am

Sophie Quinn posted a blog.

Alternative biochemical markers

Even though the above-mentioned decision thresholds for pleural pH or glucose are commonly used to screen for CPPE, the evidence supporting this practice comes from consensus of clinical opin-ion. In ...

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November 18, 2014 10:59 am

See 8 more posts from Sophie Quinn

Sophie Quinn posted a blog.

Tumor Necrosis Factor-а in Pleural Fluid

Thus, detection of gross pus means that patient has an empyema, which is an absolute indication for drainage. Pleural drainage will also most likely be needed for patients with positive pleural fluid ...

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November 18, 2014 10:59 am

Sophie Quinn posted a blog.

Traditional fluid chemistries

Combination of pleural TNF-a and LDH in an “or” rule, wherein the pleural space would be drained if any one of the two results are “positive,” yielded measures for sensitivity (91%; 95% CI, 78 to 100%...

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November 18, 2014 10:58 am

Sophie Quinn posted a blog.

TNF-a

Various cutoff levels of TNF-a were tested for the identification of CPPE, and 80 pg/mL yielded the best results (Table 2). This corresponded to a sensitivity, specificity, and accuracy of 78%, 89%, a...

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November 18, 2014 10:57 am

Sophie Quinn posted a blog.

PPE

Finally, a bivariate correlation analysis (Pearson) was used to test for significant linear relationship between polymorphonuclear leukocyte counts and levels of TNF-a in pleural fluid. A two-tailed p...

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November 18, 2014 10:56 am

Sophie Quinn posted a blog.

Pleural fluid

Separated specimens were collected in tubes containing ethylenediamine tetra-acetic acid, centrifuged at 1,500g for 15 min at 4°C, and the superna-tants were stored at - 70°C until TNF-a analysis. Onl...

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November 18, 2014 10:54 am

Sophie Quinn posted a blog.

Tumor necrosis factor

Tumor necrosis factor (TNF)-a plays a key role in the inflammatory response. A unique study by Odeh et al showed that pleural fluid levels of this cytokine were significantly higher in CPPE than in UP...

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November 18, 2014 10:54 am

Sophie Quinn posted a blog.

Parapneumonic effusions

Parapneumonic effusions (PPEs) occur in approximately 40% of patients who require hospital admission for bacterial pneumonia, and represent the second most common cause of exudates, exceeded only by m...

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November 18, 2014 10:53 am

Sophie Quinn posted a blog.

Pediatric Bronchoscopy

Many bronchoscopists routinely administer atropine prior to each procedure. Is this of benefit, or should we wait for the occasional vasovagal reaction before administering the drug? Also, there are n...

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November 18, 2014 10:53 am

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